Bio-k+ 50 billion probiotic capsules help to reduce the risk of antibiotic-associated diarrhea and optimizes intestinal flora health. Each capsule features targeted release technology, with an enterosoluble coating, ensuring that their component bacteria survive their passage through the intestinal tract. Features:helps support intestinal and gastrointestinal health. Helps reduce the risk of antibiotic associated diarrhea and clostridium difficile associated diarrhea. Helps normalize stools. Enteric coated. Vegetable capsule.refrigeration requireddosage: 1-2 capsules daily. If you are taking antibiotic(s), take bio-k+ 2 or 3 hours after antibiotics.ingredients: lactobacillus acidophilus cl1285, lactobacillus casei lbc80r, lactobacillus rhamnosus clr2 non-medicinal ingredients: cellulose, hypromellose, yeast extract, dextrose, ascorbic acid, magnesium stearate, ethylcellulose, sodium alginate, silicon dioxide, medium chain triglycerides, titanium dioxide. Caution: do not use if you are experiencing nausea, fever, vomiting, bloody diarrhea or severe abdominal pain. Do not use if you have an immune-compromised condition (e.g. Aids, lymphoma, patients undergoing long term corticosteroid treatment). If symptoms of digestive upset (e.g. Blood in the stool) occu, worsen or persist, consult a health care practitioner. Do not use if seal is broken. Keep out of reach of chlidren 5 years and younger.