Preparation h suppositories provide prompt soothing relief from internal swelling, burning, itching and discomfort. Preparation h suppositories provide effective nighttime relief, and protect irritated tissue. Regular application with preparation h suppositories provides continual therapy for relief of hemorrhoidal symptoms.features: reduces internal hemorrhoidal swelling perfect for nighttime hemorrhoidal symptom relief soothes painful burning, itching and discomfort shrinks swollen hemorrhoidal tissue directions: remove suppository from foil wrapper. Insert one suppository into the rectum in the morning, at night, after each bowel movement and whenever symptoms occur. Children under 12 years of age: consult a doctor. Caution: if the condition persists or in case of bleeding, a physician should be consulted. May stain clothing. Keep safely out of the reach of children. Store at room temperature (15Â°-30Â°c). Medicinal ingredients: yeast as a live cell derivative (bio-dyne: skin respiratory factor) 22.0 mg.non-medicinal ingredients: chlorhexidine gluconate, cocoa butter, glycerin, polyethylene glycol, water, wax, witepsol.