Philips avent anti-colic baby bottle medium flow nipple lets babies control the flow of milk like with breastfeeding, which can reduce spit-up and overeating. Philips avent’s anti-colic valve flexes to keep air in the bottle and out of your baby’s tummy, a feature that reduces fussing and colic. In a clinical trial, two-week-old infants fed with a philips avent anti-colic baby bottle bottle experienced less colic than babies fed with a conventional bottle, with the greatest difference seen at night. Designed for babies at least 3 months old, these three-hole nipples offer a medium flow. The nipple is made of flavorless, odorless silicone that resists discoloring and stickiness. The nipple’s soft, rounded shape promotes feeding for babies who nurse from both the breast and a bottle.features:nipple features 3 holes ideal for babies 3 months old and up clinically proven to reduce colic philips avent classic+ and anti-colic bottles and nipples are compatible. Anti-colic bottles can be used with classic+ nipples and classic+ bottles can be used with anti-colic bottle nipples. Bpa-free dishwasher safe.